How to Build Agentic RAG
Nov 13, 2025
RAG retrieves documents.
Agentic RAG decides what, why, and when.
One searches. The other reasons strategically.
Let me break this down in a way that'll
save you months of trial and error.
》What Makes Agentic RAG Different?
Traditional RAG is like asking a librarian for one book.
They hand it over, and you're done.
Agentic RAG?
That's your research team that:
✸ Routes queries across 7+ databases simultaneously
✸ Breaks complex questions into sub-tasks automatically
✸ Cross-references conflicting sources before answering
✸ Iterates until the answer is actually complete
The difference isn't subtle. It's transformational.
》The Numbers Don't Lie
✸ Radiology diagnostic accuracy jumped from 68% to 73% using Agentic RAG systems in recent clinical studies.
✸ That 5% isn't a minor improvement. It's lives saved every single day.
✸ Google reduced enterprise search time by 50% with Agentic RAG.
What took employees hours now completes in seconds.
✸ IBM Watson cut document review time in half for healthcare and legal sectors using these systems.
These aren't pilots.
They're production systems processing millions of queries.
》When You Actually Need Agentic RAG
Three clear signals:
→ Your queries require multi-step reasoning across sources
→ Data lives in multiple databases with different structures
→ Context changes dynamically and requires real-time adaptation
If you're in healthcare, finance, legal, or any regulated industry handling
complex compliance? This isn't optional anymore.
》Single-Agent vs Multi-Agent Architecture
Look at the visual I've shared above.
Single-agent RAG queries one database and stops. Multi-agent Agentic RAG orchestrates 4+ specialized agents checking 7+ sources simultaneously.
✸ That's not an incremental upgrade.
✸ That's architectural evolution.
✸ One agent handles routing.
✸ Another validates retrieval quality.
✸ A third cross-checks for hallucinations.
✸ A fourth synthesizes the final answer.
This is how production systems actually scale.
》The Frameworks That Matter
Since I teach LangGraph, CrewAI, PydanticAI, OpenAI Swarm, and MCP to developers worldwide, here's what works:
✸ LangGraph excels at state management across agent reasoning cycles
✸ CrewAI dominates multi-agent orchestration with role-based delegation ✸ PydanticAI ensures type-safe, validated outputs from agents.
✸ OpenAI Swarm offers lightweight agent handoffs with minimal overhead ✸ MCP standardizes how agents connect to data sources
Each framework solves different patterns.
Knowing which one to use separates systems that work from systems that scale.
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👩💻 Written by Dr. Maryam Miradi
CEO & Chief AI Scientist
I train STEM professionals to master real-world AI Agents.
